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turnitin software free download turnitin software download full version turnitin software crack turnitin software serialkey turnitin software full downloadNovel immunosuppressive mechanism of (-)-epigallocatechin-3-gallate in chronic graft-versus-host disease.
(-)-Epigallocatechin-3-gallate (EGCG), the main dietary polyphenol in green tea, has potent anti-inflammatory effects. Its immunosuppressive potential in chronic graft-versus-host disease (cGVHD) remains largely unknown. This study aimed to investigate the effect of EGCG on cGVHD in mice. We found that oral administration of EGCG to mice together with Lewis lung carcinoma-transplanted mice caused significant reduction of cGVHD severity. EGCG inhibited the expansion and function of CD4(+)CD44(+) T cells, and the production of interleukin (IL)-17, tumor necrosis factor-α and interferon-γ in splenocytes and serum. Moreover, EGCG suppressed the expression of phosphorylated signal transducer and activator of transcription-1 in CD4(+) T cells and IL-17-producing CD4(+) cells in vivo. Finally, in cGVHD mice, the injection of EGCG significantly reduced the frequencies of IL-17-producing cells and IL-17 production in the spleens and sera. These results indicate that EGCG may be a new candidate drug to treat cGVHD.Ole Henning Ørvig

Ole Henning Ørvig (25 January 1796 – 3 August 1877) was a Norwegian politician and businessman.

Personal life
He was born in Christiania as a son of merchant and politician Ove Ørvig and Ørvig Magdalene. He was a half-brother of Thomas Ørvig and a granduncle of A. Ørvig. He attended the polytechnic school from 1813 to 1814, and the Royal Military Academy from 1818 to 1819. He also studied economy for one year in London. He was married in 1824 to Sigrid Lallen, with whom he had several children. He was an ancestor of Hans Aanestad.

Career
After finishing his studies, he worked for some years as a broker and was the director

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